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大蒜素

分析標(biāo)準(zhǔn)品,98%(鑒別)

Allicin

CAS號：539-86-6

MDL：MFCD00468100

產(chǎn)品介紹

Allicin (diallyl thiosulfinate)，一種大蒜提取物，包含 Diallyl monosulfide、Diallyl disulfide、Diallyl trisulfide、Diallyl tetrasulfide、Methyl allyl disulphide 等，占據(jù)混合物總和的 98%。Allicin (diallyl thiosulfinate) 含有高效抗菌活性，能夠抑制多種微生物生長，其中包括抗抗生素菌株。

沸點：248.6 ℃ at 760 mmHg

外觀：透明至略黃色液體

溶解性：DMSO  :  130  mg/mL  (801.13  mM;  Need  ultrasonic)

Ethanol  :  70  mg/mL  (431.38  mM;  Need  ultrasonic)

儲存條件：2-8℃

注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(43篇)

43. [IF=4.2] Yangwan Zhang et al."Allicin mitigates fumonisin B1-induced kidney toxicity in quails: Modulating fibrosis, NF-κB signaling pathway, and mitochondrial damage."POULTRY SCIENCE.2025 Aug;104:105356

42. [IF=12.7] Zhang Shiqi et al."Allicin enhances urea-N conversion to microbial-N by inhibiting urease activity and modulating the rumen microbiome in cattle."Microbiome.2025 Dec;13(1):1-17

41. [IF=5.3] Quan Xu et al."Macrophage Membrane-Coated Nanoscale Allicin for the Targeted Treatment of Drug-Resistant Bacterial Pneumonia."ACS Applied Nano Materials.2025;XXXX(XXX):XXX-XXX

40. [IF=8] Wang Xiaonan et al."Selective G6PDH inactivation for Helicobacter pylori eradication with transformed polysulfide."Science China-Life Sciences.2025 Jan;:1-16

39. [IF=8.5] Miaomiao Liu et al."The synergistic antibacterial effects of allicin nanoemulsion and ε-polylysine against Escherichia coli in both planktonic and biofilm forms."FOOD CHEMISTRY.2025 Apr;472:142949

38. [IF=4.7] Yijie Gao et al."Metagenomic Sequencing Combined with Metabolomics to Explore Gut Microbiota and Metabolic Changes in Mice with Acute Myocardial Infarction and the Potential Mechanism of Allicin."Drug Design Development and Therapy.

37. [IF=4.8] Li He et al."Dunhuang Dabupi Decoction and its active components alleviate ulcerative colitis by activating glutathione metabolism and inhibiting JAK-STAT pathway in Drosophila and mice."JOURNAL OF ETHNOPHARMACOLOGY.2025 Apr;346:119717

36. [IF=3.3] Jiang Xiuzhi et al."Essential Oils and their Active Constituents Effective against Non-growing Mycobacterium intracellulare."BMC Complementary Medicine and Therapies.2025 Dec;25(1):1-10

35. [IF=5.7] Yupei Deng et al."Allicin Improves Diet-Induced Nonalcoholic Steatohepatitis and Gut Microbiota Dysbiosis in Mice via the Involvement of the Circadian Clock Gene Rev-erbα."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2025;XXXX(XXX):XXX-XXX

34. [IF=4.3] Wang Jin-Yan et al."Allicin impacts the susceptibility of Spodoptera exigua to nucleopolyhedrovirus."JOURNAL OF PEST SCIENCE.2024 Sep;:1-11

33. [IF=6.2] Xin Jin et al."Allicin attenuates the oxidative damage induced by Aflatoxin B1 in dairy cow hepatocytes via the Nrf2 signalling pathway."ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY.2024 Jul;280:116527

32. [IF=5.2] Kelin Li et al."Allicin Promotes Glucose Uptake by Activating AMPK through CSE/H2S-Induced S-Sulfhydration in a Muscle-Fiber Dependent Way in Broiler Chickens."MOLECULAR NUTRITION & FOOD RESEARCH".2024 Feb;:2300622

31. [IF=7.2] Zhao Fang et al."Astilbin protects from sepsis-induced cardiac injury through the NRF2/HO-1 and TLR4/NF-κB pathway."PHYTOTHERAPY RESEARCH.2023 Dec;:

30. [IF=5.6] Zhibin Wang et al."Allicin ameliorates glucose and lipid metabolism via modulation of gut microbiota and bile acid profile in diabetic rats."Journal of Functional Foods.2023 Dec;111:105899

29. [IF=6.1] Lu Li et al."Allicin Alleviates Mitochondrial Dysfunction in Acrylamide-Induced Rat Kidney Involving the Regulation of SIRT1."JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY.2023;XXXX(XXX):XXX-XXX

28. [IF=3.3] Li Xiao-Jun et al."Allicin ameliorates sepsis-induced acute kidney injury through Nrf2/HO-1 signaling pathway."Journal of Natural Medicines.10.1007/s11418-023-01745-3

27. [IF=4.927] Linzehao Li et al."Allicin Alleviates Diabetes Mellitus by Inhibiting the Formation of Advanced Glycation End Products."MOLECULES.2022 Jan;27(24):8793

26. [IF=6.429] Xiwen Jia et al."Fabrication and characterization of crosslinked pea protein isolated/pullulan/allicin electrospun nanofiber films as potential active packaging material."Food Packaging and Shelf Life. 2022 Sep;33:100873

25. [IF=4.566] Wenxing Huang et al."Dietary Allicin Improved the Survival and Growth of Large Yellow Croaker (Larimichthys crocea) Larvae via Promoting Intestinal Development, Alleviating Inflammation and Enhancing Appetite."Front Physiol. 2020; 11: 587674

24. [IF=5.279] Peirong Cai et al."Quercetin and Allicin Can Alleviate the Hepatotoxicity of Lead (Pb) through the PI3K Signaling Pathway."J Agr Food Chem. 2021;69(32):9451–9460

23. [IF=5.279] Yuan Yuan et al."Allicin Ameliorates Intestinal Barrier Damage via Microbiota-Regulated Short-Chain Fatty Acids-TLR4/MyD88/NF-κB Cascade Response in Acrylamide-Induced Rats."J Agr Food Chem. 2021;69(43):12837–12852

22. [IF=5.682] Tong Gao et al."The protective effect of allicin on myocardial ischemia-reperfusion by inhibition of Ca2+ overload-induced cardiomyocyte apoptosis via the PI3K/GRK2/PLC-γ/IP3R signaling pathway."Aging-Us. 2021 Aug 15; 13(15): 19643–19656

21. [IF=0] Huinan Chen et al."Allicin Inhibits Proliferation and Invasion in Vitro and in Vivo via SHP-1-Mediated STAT3 Signaling in Cholangiocarcinoma."Cell Physiol Biochem. 2018;47(2):641-653

20. [IF=2.356] Zhi Huang et al."Thermal kinetics of enzyme inactivation, color changes, and allicin degradation of garlic under blanching treatments."J Food Process Eng. 2019 May;42(3):e12991

19.  Huang, Wenxing, et al. "Dietary allicin improved the survival and growth of large yellow croaker (Larimichthys crocea) larvae via promoting intestinal development, alleviating inflammation and enhancing appetite." Frontiers in Physiology 11 (2020).https:##

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17.  金鑫,李鴻洋,李敬雙,郭曉麗,于洋.大蒜素對小鼠腹腔巨噬細(xì)胞的抗炎作用[J].畜牧與獸醫(yī),2020,52(12):85-88.

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14.  張靜林, 王書蘭, 陶陽,等. 臭氧處理對脫水蒜片減菌效果及品質(zhì)的影響[J]. 食品工業(yè)科技, 2016, 37(17):312-315.

13.  鄧薇, 張洪, 高潔芳,等. 大蒜素聚合物膠束的制備及質(zhì)量評價[J]. 中國藥師, 2019, 022(004):759-763.

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11.  張丹丹, 田珊, 凡苗苗,等. 大蒜素對衰老模型小鼠學(xué)習(xí)記憶及抗氧化能力的影響[J]. 中國熱帶醫(yī)學(xué), 2020, 20(1).

10.  方偉, 陳景南, 范成譜,等. 大蒜素對腦膠質(zhì)瘤C6細(xì)胞增殖和凋亡的實驗研究[J]. 浙江中醫(yī)藥大學(xué)學(xué)報, 2016, 40(10):762-767.

9.  張正升, 韓貴芝, 張丹丹,等. 大蒜素對心肌缺血大鼠心肌組織CGRP及其受體mRNA表達(dá)水平的影響[J]. 中西醫(yī)結(jié)合心腦血管病雜志 2020年18卷10期, 1543-1546頁, ISTIC, 2020.

8.  韓貴芝, 張春芝, 劉翠容,等. 大蒜素對小鼠胸腺淋巴細(xì)胞周期進(jìn)程影響的實驗研究[J]. 中國預(yù)防醫(yī)學(xué)雜志, 2017, 018(012):942-944.

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6.  李希敏,徐露,周璐,邵田娛,梁珍珍.大蒜素對大鼠腎間質(zhì)纖維化干預(yù)作用及對腎組織TGF-β1/Smads信號通路的影響[J].浙江中西醫(yī)結(jié)合雜志,2019,29(10):793-796+877.

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1.  唐仕榮  陳尚龍  苗敬芝 等. 發(fā)酵大蒜加工過程中功能物質(zhì)與抗氧化活性的變化研究[J]. 中國調(diào)味品  2018(10):17-21.

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